×
Entertainment

These Infections Are Linked to 12% of New Cancer Cases

These Infections Are Linked to 12% of New Cancer Cases

Certain human papillomaviruses, or HPV, are behind the majority of cervical cancers and a number of head and neck cancers as well, says Harriet Rumgay, an epidemiologist at IARC who is an author of the new report. About 4% of new cancer diagnoses in 2024 could be attributed to HPV infection. 

Doctors and researchers have known for decades that hepatitis B and hepatitis C infections also drive many cases of liver cancer, linked to 2% and less than 1% of new diagnoses respectively, according to the report. 

There is also strong evidence linking Helicobacter pylori, a bacterium that infects the stomach and small intestine, with gastric cancers. This infection was calculated to be behind about 4% of new diagnoses. And Epstein-Barr Virus (EBV), which causes mononucleosis and affects more than 90% of the world’s population, was involved in around 1% of new diagnoses, including lymphomas, nasopharyngeal cancers, and gastric cancers. Seven other infections, including HIV, were also flagged as carcinogens in the study.   

For other infections, no vaccines are available. For EBV, a nearly ubiquitous virus with a long, clearly documented history of contributing to cancer, “we don't have an effective vaccine yet, or an effective way of preventing it,” says Rumgay. “This is something that we want to highlight with our study.” 

Historically, it was difficult to interest pharmaceutical companies in vaccines for viruses like EBV that are common and nonlethal, says Lawrence Young, a virologist and emeritus professor of molecular oncology at University of Warwick in the U.K. who has spent his career studying cancer and EBV. (Young was not involved in the IARC research.)

But thanks in part to research suggesting EBV might be involved in multiple sclerosis, an autoimmune disorder, “they've all become very interested,” he says. A number of vaccine candidates are now being studied, with some in clinical trials. 

For some of the infections implicated by the latest study—the Kaposi-sarcoma associated herpes virus, in particular—there’s need for much more research into prevention, says Rumgay. The hope is that “these new findings might stimulate more development in that area,” she says. 

Web hosting by Somee.com